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A market research report on

From the Fringes to

the Forefront:

mRNA is here to

Transform Global

Health

mRNA: The Understanding

Discovered in 1960, mRNA stands for “messenger ribonucleic acid” or “messenger RNA”; basically the mRNA is

software of life

Advantages of mRNA:

•

Speed of design and scalability of manufacturing mRNA over other vaccines and therapies has a very major advantage DNA

mRNA

Protein

•

Another advantage that mRNA may offer over other more traditional vaccine types (such as live attenuated vaccines, inactivated vaccines and sub-unit vaccines) and over DNA based Software

Application

Storage

vaccines is safety

mRNA is a

Proteins form the

•

mRNA is non-infectious and non-integrating DNA stores

temporary set of

basis of life by

(i.e. it does not cause DNA insertions) which instructions for

instructions for

performing the

gives it a further advantage over attenuated proteins in the

cells to make a

function required

and DNA based vaccines

nucleus

protein

by every cell

mRNA Becomes the Rising Star of Nucleic Acid Therapy How does the mRNA works?

Cellular machinery

mRNA provides genetic

follows the mRNA

Viral proteins induce

Antibodies are ready to instructions to make

instructions to produce

an immune response

combat viral infection

viral proteins

•

After decades of research and the accumulation of theoretical knowledge, the COVID-19 pandemic in early 2020 brought mRNA to the forefront as a new modality, and finally reached the tipping point in demonstrating its utility in infectious diseases

•

mRNA vaccines, upon delivery, tell our cells to synthetize proteins, e.g., resembling those from the coronavirus (the SARS-Cov-2

spike proteins)

•

This cellular generation of proteins then elicits an immune response in which the body produces virus-neutralizing antibodies even before infection with the real pathogen 3

mRNA made Headlines in 2020

Moderna is a leader in mRNA technology mRNA made headlines in December 2020 when one of the world’s first COVID-19 vaccines, developed by US-based pharmaceutical company Moderna, the National Institute of Allergy and Infectious Diseases (NIAID), and the Biomedical Advanced Research and Development Authority (BARDA), began rolling out to members of the public Moderna’s vaccine was developed at unprecedented speed, and its public launch marked a turning point in the pandemic. By the end of last year, the company had shipped more than 800 million vaccines worldwide, with approximately 25 percent shipped to low-to-middle income countries through direct sales or donations The Company’s mRNA platform is intrinsically flexible, allowing the company to move mRNA medicines quickly from idea to development candidate nomination. This means it can be used to contain future COVID outbreaks and manage yearly mutations, staying ahead of the virus’ evolution The company’s manufacturing platform was designed so that it would not need to amend production processes to produce new boosters or mRNA vaccines

mRNA Therapies: Clinical Pipeline Assets Line Items Split by Therapeutic Areas Line Item Split by Clinical Phase 44

Assets

Unique

Products

Companies

Who should buy this report?

Pharmaceutical

HealthTech

Digital Health

MedTech

Other Lifesciences

Players

Companies

Entities

Players

Companies

Topics of Upcoming Reports

Will the Expiry of Humira Market Exclusivity and Entry of its Biosimilars Move the Needle in BioPharma Market?

From the Fringes to the Forefront: mRNA is here to Transform Cost of this report:

Global Health

Melting the Iron Triangle: 10 Healthcare Players aiming Beyond $2,500

Health Equality to Conquer Health Equity Robotics: Embarking a New Era in Surgical Innovations Annual Subscription:

Metaverse: Paving the way for Health 4.0

$125,000 $60,000

Healthcare Future Outlook 2023

Patient Engagement- a New Standpoint on Care that is (Includes a total of 50 reports) Patient-Centered

E-Rx, the Digital Version of Prescription Improvising the Chances of Better Patient Outcomes

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Integration of Healthcare Systems with Big Data and Data Silos

Methodology & Scope

Research Methodology

▪ Insights 10’s research methodology delves deeper into the market, covering the macro and micro aspects of the industry. We identify the key growth drivers, opportunities, and restraints that might promote or hinder the future industry growth along with an expansive overview of the competitive landscape to help our clients make informed strategic decisions

▪ We implement a mix of primary and secondary research for our market estimate and forecast. The secondary research forms the initial phase of our study where we conduct extensive data mining, referring to verified data sources such as independent studies, government and regulatory published material, technical journals, trade magazines, and paid data sources

▪ For forecasting, the following parameters are considered:

❑

Market drivers and restraints along with their current and expected impacts

❑

Technological scenario and expected developments

❑

End use industry trends and dynamics

❑

Trends in the consumer behavior

❑

Regulatory scenario and expected developments

❑

Current capacity and expected capacity additions up to 2030

▪ We assign weights to these parameters and quantify their market impacts using the weighted average analysis to derive the expected market growth rate

▪ We appoint data triangulation strategies to explore different areas of the market. Our qualitative and quantitative assessments are time-sensitive, reflecting the most recent value and volume of the market across regions

▪ All our estimates and forecasts are verified through exhaustive primary research with the Key Industry Participants (KIPs)

▪ Currency used in the report is the US dollar (USD), with the market size indicated in USD million/billion (Mn/Bn)

Analysis Methodology

Our Analysis Methodology involves three critical stages: Data Collection

Market Data Analysis

Interpretation &

& Statistical Model

Presentation

Analysis &

Market Trends

Secondary

Interpretation

Research

Market Sizing &

Insights

Primary

Analysis

Research

Data Triangulation &

Presentation &

Validation

Reporting

Data Triangulation & Data Validation Top Down Approach

Final

Final Market size break up to Market

rest of segmentation

Size

Validation from

Arriving at market size

Primary Interview

of each segment

Approach

Summarization of revenue

Approach

generated from companies

Validation from

to arrive at total market size Primary Interview

Bottom Up

op Down

Revenue generated by products & Final

services offered by companies Summary

Bottom Up Approach

Key Benefits for Stakeholders from this Report Study provides an in-depth analysis of the market with current trends and future estimations to elucidate the imminent investment pockets

Our tools provides stakeholders with a cohesive understanding of the industry outlook, considering the qualitative and quantitative industry variables Comprehensive analysis of factors that drive and restrict the market growth is provided Comprehensive quantitative analysis of the industry from 2021 to 2030F is provided to enable the stakeholders to capitalize on the prevailing market opportunities Extensive analysis of the key segments of the industry helps understand the applications and technologies used globally Our rigorous data collection, thorough statistical analysis and specialist assessments ensure that our clientele has a greater understanding of the industry space, supply chain, price fluctuations, competitive landscape, and other vital factors 12

Time Frame

Report Attribute

Details

Quantitative Units

Revenue in USD Million/Billion (Mn/Bn) Base Year for

2021

Market Overview, Revenue Forecast, Market Estimation

Report Coverage

Segmentation, Growth Factors and Trends, Company Profiles, Competitive Landscape, Regulatory Landscape, Future Opportunities Report Customization (5 working days) with Customized Report

purchase. We will provide you with data that is currently not a part of our scope as a part of 2022-Forecast

customization

2030

Period

Pricing and purchase

Avail customized purchase options to meet options

your exact research needs

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This report presents data, which is: Reliable

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Real

Comprehensive

Easy to read

The report is prepared

The data is prepared by

Allowing you to

Covers everything you

You do not have to be a

using a proven

a team of highly qualified

confidently make

would need to know

market expert to

methodology and

& experienced research

smarter business

about the market

understand what really is

insightful research

analysts & vetted by our

and strategic

including market size,

happening on the market

local associates

decisions

competitive analysis &

and how it works

much more

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can trust

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Insights10 is a healthcare focused market research firm founded with an aim of being an insights driven company in the data driven world and delivering actionable insights that can drive decision and strategy making process for businesses

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Identification of

Market

Collection of

Collaboration

Verification &

Data

Dynamics

Data

of Data

Analysis

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Statistical Databases

Company Websites/Annual Reports Data

Trade Publications

Sources

We have access to multiple highly Online Databases

reliable free and subscription data sources. We have many years of Published Research Reports

experience to understand which sources are more dependable for what Whitepapers

and which to prefer for the reliable and latest information.

Press Releases of Key Market Players

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Over the years, we have developed an in-depth experience of executing market analysis at global, regional & country specific level in life sciences.

Our team has

conducted market

research across 62+

global markets in

America, Europe,

Middle East, Africa and

Asia Pacific regions

Research Projects Done

Project Leadership Team

Dr. Purav Gandhi

Mukesh Nayak

Ritu Baliya

Dhruv Joshi

Founder & CEO

Head - Marketing

Engagement Manager

Consultant

Purav is a physician and an

Mukesh is an engineering graduate Ritu has over 6 years of experience in Dhruv Joshi is an engineer and has done entrepreneur with 12+ years of with an MBA in Marketing. He is a strategy building, market assessments, Masters in Hospital Administration with experience in Healthcare & Life seasoned healthcare market

market sizing, and RWE for global MNC

over 4 years of experience in the Sciences industry spanning across research & marketing professional healthcare & biopharma clients across healthcare and life science industry. He strategy, market access, health with a progressive experience of over diff. markets (America, Europe, Africa, has gained proficiency in market informatics and RWE, Digital

20 years in Life Sciences, Pharma APAC and Middle East). Her areas of research, market assessment, and Healthcare, analytics and data science.

and Medical Device sectors . With an expertise include: Indentifying emerging developing insights from it. He has Purav studied medicine from Gujarat in-depth understanding of primary trends in life sciences industry, worked on various consulting projects University and also completed his MBA research, he has conducted

Competitor landscape assessment, across different geographies including from IIM-Kozhikode. Purav started his hundreds of interviews of various Disease opportunity assessments etc.

Asia, Europe, US, MENA. He has been career with Deloitte working on strategy stakeholders in pharma & healthcare She is a pro in secondary and primary aligned in working for sector reports of consulting engagements and also

& completed several research research with a deep domain expertise various geographies along with market co-founded ConvergeHealth by projects across life sciences industry.

in healthcare sector.

sizing and forecasting.

Deloitte.