Supplementing with 50-200 mcg of selenium and 200-400 I.U. of Vitamin E has been shown to improve clinical
symptoms and signs in patients with rheumatoid arthritis. Glutathione peroxidate enzyme is especially important in
activating the anti-inflammatory prostaglandins and leukotrienes.19,20 Other inflammatory conditions may also
benefit from Vitamin E and selenium supplementation such as other forms of arthritis, eczema and psoriasis, where
selenium and glutathione peroxidase levels are often low.21,22 In a German study, 200 mcg of selenium significantly
improved signs and symptoms of rheumatoid arthritis and patients required less anti-inflammatory medications and
cortisone. Less tender joints and morning stiffness were reported by the subjects receiving the selenium. Placebo
subjects did not report the same benefits.23
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