A study of 25 cross-country skiers has provided preliminary evidence that CoQ10 supplementation may improve
exercise performance in endurance athletes.25
Sedentary individuals have also demonstrated improvement with work capacity, oxygen consumption, fat burning and
oxygen transport after beginning an exercise program. The group supplemented with CoQ10 demonstrated greater
improvement in these aerobic parameters compared to the placebo group, in a 4-8 week trial period.26
Dosage Ranges
1. Cardiovascular Conditions: typical dosage is 50-60 mg, three times per day. Large doses (up to 300 mg) may be
needed in severe heart disease. Some studies use a dosage of 2 mg CoQ10 for each kilogram of body weight.
2. Periodontal Disease: 50 mg per day has been used in clinical trials
3. Exercise Performance Studies: 60 mg per day27
Toxicity and Contraindications
Coenzyme Q10 is well tolerated, and no serious adverse effects have been reported with long-term use.27
Drug-Nutrient Interactions